Explain the response to this safety concerns by changing the policy to control these meds and write about this controlling worldwide (US, EU, UK, SAUDI, other countries) any word that controlled these meds.

Dear writer these are the main outline that need to be explained within the writing as follow:
1- What are gabapentinoid (pregabalin and gabapentin)
2- Pregabalin and gabapentin uses and indication
3- The reason for the increasing in the pregabalin and gabapentin utilization (prescriiptions and doses).
4- Gabapentinoid (pregabalin and gabapentin) related safety in general around the world and the UK I particular. (Safety contain: adverse effect, overdose, misuse, death, and the use of pregabalin and gabapentin in treatment of pain (off label).
5- Explain the response to this safety concerns by changing the policy to control these meds and write about this controlling worldwide (US, EU, UK, SAUDI, other countries) any word that controlled these meds.